Biophysics of the Cell – Tutorial
For further questions about talks, dates and lecture contents, please contact the supervisor of the tutorial:
Janina Lange firstname.lastname@example.org
23. Oct.: No tutorial, continuation of lecture
30. Oct.: No tutorial, discussion with guest lecture
13. Nov.: No tutorial, continuation of lecture
27. Nov.: No tutorial, continuation of lecture
11. Dec.: No tutorial, continuation of lecture
8. Jan.: Block seminar: student presentations (no lecture)
15. Jan.: Block seminar: student presentations (no lecture)
29. Jan.: EXAM
5. Feb.: No tutorial, continuation of lecture
The links to publications below each topic give an example of a paper that can be used to provide information, graphs or images about the topic. However, the students will be asked to do their own research on background knowledge, and not solely depend on this publication. Your talk should roughly consist of 66% technical background, and 33% applications of the technique.
Each seminar talk is supposed to be 15min long, followed by a 5min discussion with the group.
All seminar talks have to be given in English.
Each one of you has the possibility to show me or a colleague your slides in December (on Mondays before the lecture, so on 4th, 11th or 18th Dec.). You can ask open questions for roughly 10min. For this appointment, please send me an email to fix a date. For the appointments, meet me in the living room of Lehrstuhl Rädler, 1st floor, room NZ033.
Here is the final talk schedule (2018/01/08): please check if you are part of it and send me a note if we haven't included you yet.
2018/01/16: If you want to know your grades, please send me (Janina) an email and explicitely ask for them!
1) Superresolution microscopy applied to lipid membranes: imaging lipid rafts
2) Small angle X-ray scattering: the structure of lipid double layers
3) Cryo-TEM: nobel prize 2017 and its application to biological membrane
4) Dynamic Light Scattering: Artificial cells
5) Micropipette aspiration: tether formation of cell membranes
6) Gene delivery: lipid-DNA carrier complexes
7) Ultra short time spectroscopy: electron transfer during photosynthesis
8) Förster-Resonance Energy Transfer (FRET): a molecular ruler
9) Dye-sensitized photovoltaic cell
Block II: Nerve cells
10) Patch-Clamp: its historical role in neuroscience
K. v. Grafenstein
11) Chip-based patch-clamp technologies: high throughput drug screening
12) Atomic force spectroscopy: measuring the mechanical properties of axonal cones
13) Magnetic resonance imaging: detecting multiple sklerosis
14) Imaging with carbon nanotubes through-skull
Cell migration and mechanics
15) Particle Image Velocimetry (PIV): investigation of collective cell migration
16) Thermal noise imaging: geometry of collagen networks
17) 2D traction force microscopy on the single cell level
18) Traction force microscopy in 3D: cell migration in 3D networks
19) Magnetic tweezers: measurements of cell plasticity
20) Pillar assay: measurements of cardiac contractility
21) Cell stretcher: cell orientation along strain and stress gradients
22) Optical stretcher: contact-free measurements of cell mechanical properties
23) Real-time deformability cytometry: whole-blood sorting through cell mechanical properties