Modelling mechanical properties of DNA and RNA
Prof. Dr. Filip Lankas (The Czech Academy of Sciences, Prague, Czech Republic)
Structure and elasticity of nucleic acids play a role in many biological processes, including replication, gene regulation and chromatin organization in the cell. They are also important for designing artificial DNA and RNA nanostructures. The talk will focus on formulating suitable models of nucleic acids mechanics and inferring the model parameters from large-scale computer simulations of molecular dynamics. Connection to experiment and applications of the results will be discussed.