Cell stiffness and cell volume
Prof. Dr. Dave Weitz (School of Engineering and Applied Sciences/Department of Physics Harvard University, Cambridge, USA)
The stiffness of cells is commonly assumed to depend on the stiffness of their surrounding: bone cells are much stiffer than neurons, and each exists in surrounding tissue that matches the cell stiffness. In this talk, I will discuss new measurements of cell stiffness, and show that that cell stiffness is strongly correlated to cell volume. This affects both the mechanics and the gene expression in the cell, and even impacts on the differentiation of stem cells.