Fakultät für Physik




Seminar: Physics of Evolution – Übersicht

  • Übersicht

Which biophysical processes could lead to the first living systems? Can we build life from bottom up in the lab? The minimal requirements for the emergence of an evolutionary dynamics are three processes: replication, mutation, and selection. To maintain the genetic simulation, also a nonequilibrium system is needed. We will discuss recent progress in understanding this phase transition from nonliving to living matter. Topics will include experimental and theoretical treatments and advances.

Informationen zur Vorlesung

Zeit und Ort

Zeit und Ort
Fr. 12.30-14.00
H206 Schellingstr. 4

The Seminar is geared towards Masterstudents, however talented, late Bachelorstudents willing to digg deep into more special concepts are also welcome. Papers will focus on recent advances on the topic (last 4 years) and include theoretical treatments and also reviews of experimental methods.

Prof. Dieter Braun
(email: dieter.braun@lmu.de)


Topics: (ZIP of Papers - you might need to rename file to xxx.pdf.tar.gz after download - thanks to fxxxing Fiona)

1 Overview and problems of the RNA World
2 The Sutherland Pathway towards Nucleotides
3 (Almost) Dry polymerization of Nucloetides
4 Improving the stacking interactions of RNA
5 The clay perspective: surface bound catalysis
6 Understanding Thermphoresis: capacitor model and Seebeck effect
7 Escalation of Polymerization in a Trap (old and new paper)
8 Entropic DNA Machines
9 Introduction to DNA Origami
10 Mechanical Replication with a DNA tiles
10.2 Stable folding vs. Template ability
11 Probing sexual evolution in Yeast
12 Replication and Compartments
13 Evolutionary Networks
14 Replication Cellular System using Translation
15 Replication and Selection by a thermal gradient
16 Chemistry and Physics towards Translation




17 Todor Krastev (Topic 1)

24 Julia Riegger (Topic 2)

31 Alexander Borwac (Topic 4)


7 Allison Pinto (Topic 5)

14 Thomas Rind (Topic 8)

21 Michael Hartmann (Topic 9)

28 Laura Lechtenberg (Topic 10)


5 Cornelia Klinghammer (Topic 11)

12 Synthetic Evolution (Braun Lab)

19 Aleksej Belizki (13)


9 Alina Fedorchuk (Topic 12)

16 Jonas Kramer (15)

23 A thermal origin of translation - the tRNA world (Braun Lab)

30 Small surprise - we will have a "talk"

Verantwortlich für den Inhalt: Dieter Braun